High Levels of Both n-3 and n-6 Long-Chain Polyunsaturated Fatty Acids in Cord Serum Phospholipids Predict Allergy Development

BACKGROUND Long-chain polyunsaturated fatty acids (LCPUFAs) reduce T-cell activation and dampen inflammation. They might thereby counteract the neonatal immune activation and hamper normal tolerance development to harmless environmental antigens. We investigated whether fatty acid composition of cord serum phospholipids affects allergy development up to age 13 years. METHODS From a population...

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Very long chain n-3 and n-6 polyunsaturated fatty acids bind strongly to liver fatty acid-binding protein.

Synthesis of n-3 and n-6 very long chain-PUFAs (VLC-PUFAs) from 18-carbon essential fatty acids is differentially regulated. The predominant product arising from n-3 fatty acids is docosahexaenoic acid (22:6n-3), with the liver serving as the main site of production. The synthetic pathway requires movement of a 24-carbon intermediate from the endoplasmic reticulum to peroxisomes for retroconver...

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N-3 long-chain polyunsaturated fatty acids for optimal function during brain development and ageing.

We and others have demonstrated that provision of n-3 long chain polyunsaturated fatty acids (n-3 LCPs) in preterm and term babies is associated with retinal electrical responses to light stimuli, and to brain cortex related visual acuity maturation, that are similar to those observed in human milk fed infants. Our follow up results in young children suggest that neurodevelopment and cognitive ...

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Effects of enriched Artemia with n–3 long-chain polyunsaturated fatty acids on growth performance, stress resistance and fatty acid profile of Litopenaeus vannamei postlarvae

A 15-day study was conducted to evaluate the effects of Artemia metanauplii enriched with two commercial supplements (Easy DHA-Selco and S. presso) which contained high levels of n–3 long chain polyunsaturated fatty acids (n–3 LC-PUFA) on growth performance, stress resistance and fatty acid profile of Litopenaeus vannamei post larvae (PL). In this regard, PL were fed with three different types ...

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Effects of enriched Artemia with n–3 long-chain polyunsaturated fatty acids on growth performance, stress resistance and fatty acid profile of Litopenaeus vannamei postlarvae

A 15-day study was conducted to evaluate the effects of Artemia metanauplii enriched with two commercial supplements (Easy DHA-Selco and S. presso) which contained high levels of n–3 long chain polyunsaturated fatty acids (n–3 LC-PUFA) on growth performance, stress resistance and fatty acid profile of Litopenaeus vannamei post larvae (PL). In this regard, PL ...

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High Levels of Both n-3 and n-6 Long-Chain Polyunsaturated Fatty Acids in Cord Serum Phospholipids Predict Allergy Development

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